MUPIROCIN OINTMENT USP

Description

General Information:

Mupirocin (previously known as pseudomonic acid A) is a topical antibacterial ointment effective against gram-positive and gram-negative bacteria, including Methicillin-Resistant Staphylococcus Aureus (MRSA). It exhibits highly potent bactericidal action against major skin pathogens.

Mechanism of Action (MOA):

Mupirocin acts by competitively inhibiting the enzyme isoleucyl transfer RNA synthetase, preventing the incorporation of isoleucine into bacterial proteins, thus inhibiting protein synthesis and killing bacteria.

Indications:

For dermatologic use only in:

• Furunculosis

• Impetigo

• Folliculitis

• Infected eczema

• Ecthyma

• Skin infections in the elderly, including leg ulcers

• Minor wounds and minor burns

• Prevention of infections in abrasions, wounds, and small cuts

Dosage:

• Apply to the affected area three times daily for up to 10 days.

• Patients not responding within this period should be evaluated by a healthcare provider.

Contraindications:

• Hypersensitivity to mupirocin or any component of the ointment.

• Not for ophthalmic or intranasal use.

Adverse Effects:

• Localized burning sensation, itching, stinging, and dryness at the site of application.

• Rarely, cutaneous sensitization may occur.

Storage Conditions:

• Store between 20°C to 25°C.

• Do not freeze.

• Keep out of the reach of children.

Presentation:

Available in 15g Lami tube packed in a printed carton.